Handbook of Small Animal Imaging: Preclinical Imaging, Therapy, and Application
by George C. Kagadis, Nancy L. Ford, Dimitrios N. Karnabatidis, George K. Loudos
April 2016
The use of small animal models in basic and preclinical sciences constitutes an integral part of testing new pharmaceutical agents prior to their application in clinical practice. New imaging and therapeutic approaches need to be tested and validated first in animals before application to humans.
Handbook of Small Animal Imaging: Preclinical Imaging, Therapy, and Applications collects the latest information about various imaging and therapeutic technologies used in preclinical research into a single source. Useful to established researchers as well as newcomers to the field, this handbook shows readers how to exploit and integrate these imaging and treatment modalities and techniques into their own research.
The book first presents introductory material on small animal imaging, therapy, and research ethics. It next covers ionizing radiation and nonionizing radiation methods in small animal imaging, hybrid imaging, and imaging agents. The book then addresses therapeutic research platforms and image quantification, explaining how to ensure accurate measurements of high-quality data. It concludes with an overview of many small animal imaging and therapy applications that demonstrate the strength of the techniques in biomedical fields.
- Covers all aspects of preclinical imaging, from initiating a research program using animals to analyzing imaging data and methods
- Provides practical information on animal ethics, models, and handling to assist researchers in planning and executing their small animal imaging studies
- Explains how to measure and quantify images
- Explores a broad spectrum of disease types and disease sites where small animal imaging and therapy are currently applied, including cardiovascular disease and intracellular targets
